Tuberculosis
Tuberculosis (TB) is a contagious and potentially serious infectious disease caused by the bacterium Mycobacterium tuberculosis. It primarily affects the lungs but can also affect other parts of the body, such as the kidneys, spine, and brain.
TB spreads through the air when an infected individual coughs, sneezes, or speaks, releasing tiny droplets containing the bacteria into the air. When a person inhales these droplets, they can become infected with TB. However, it’s important to note that not everyone infected with the bacteria develops active TB. In many cases, the immune system is able to keep the bacteria in check, causing the infection to remain latent.
Latent TB infection means that the bacteria are present in the body but are inactive and do not cause any symptoms. People with latent TB are not contagious and cannot spread the disease to others. However, if the immune system becomes weakened, such as due to certain medical conditions or medications, latent TB can become active.
This magazine contains content which is gathered, validated, categorized, and supplied using a novel big data cyberinfrastructure technology that continually learns about Tuberculosis.
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Publication date: Feb 05, 2026 Rifampicin is one of the most effective anti-tuberculosis drugs. However, ...
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Clinical, laboratory, and MRI features differentiating tuberculous and pyogenic spondylodiscitis: a propensity score-matched analysis.
Publication date: Feb 05, 2026 Open Access PDF Concepts Keywords Laboratory Differential Diagnosis Matched Magnetic ... -
FLASH-MM: fast and scalable single-cell differential expression analysis using linear mixed-effects models.
Publication date: Feb 05, 2026 Single-cell RNA sequencing (scRNA-seq) enables detailed comparisons of gene expression ... -
Estimating the global burden of viable Mycobacterium tuberculosis infection: A mathematical modelling study.
Publication date: Feb 05, 2026 Estimating the proportion of individuals currently infected with Mycobacterium tuberculosis ... -
Ly6G granulocytes-derived IL-17 limits protective host responses and promotes tuberculosis pathogenesis.
Publication date: Feb 05, 2026 The protective correlates of Mycobacterium tuberculosis (Mtb) infection-elicited host immune ... -
Impact of three-month tuberculosis preventive treatment (3HP) on IVF-ET outcomes in infertile women with tuberculosis infection: a retrospective before-after study.
Publication date: Feb 06, 2026 This retrospective before-after study aimed to evaluate whether tuberculosis preventive ... -
Patients with tuberculosis and diabetes show altered clinical and biochemical parameters during anti-TB treatment.
Publication date: Feb 04, 2026 Type-2 diabetes mellitus (DM) increases tuberculosis (TB) risk and can ... -
Sustained regression of a tislelizumab-reactivated tuberculous focus after short-course therapy: a case report.
Publication date: Feb 04, 2026 Open Access PDF Concepts Keywords Drugs Immune checkpoint inhibitor Reactivated ... -
Blood-based cepheid 3-gene host response test for TB disease: diagnostic performance at a specialized respiratory hospital in China.
Publication date: Feb 04, 2026 Open Access PDF Concepts Keywords China 3-Gene signature Disease Cepheid ... -
Attributable societal cost of antimicrobial resistance in Ghana: a microsimulation study focusing on sociodemographic groups.
Publication date: Feb 04, 2026 We performed a microsimulation analysis predicting the societal cost of ... -
Concerted Deoligomerization and Nonfunctional Reassembly of the Hexameric Proteasomal ATPase Mpa upon Chemical and Thermal Perturbation.
Publication date: Feb 03, 2026 Mycobacterium tuberculosis Mpa is an AAA+ ATPase that unfolds and ... -
Effects of the COVID-19 Pandemic on Tuberculosis Outcomes in the United States: A Bayesian Analysis.
Publication date: Feb 04, 2026 Tuberculosis (TB) notifications and deaths in the United States fluctuated ... -
4-[(Aryloylhydrazineylidene)methyl]-N-phenylbenzamides as a new class of antimycobacterial agents: design, synthesis and biological evaluation.
Publication date: Mar 01, 2026 A novel series of 4--N-phenylbenzamides was designed, synthesized, and evaluated ... -
2-Aminothiophene and 2-aminothiazole scaffolds as potent antimicrobial agents: Design, synthesis, biological evaluation, and computational insights.
Publication date: Mar 01, 2026 The development of new antitubercular drugs is critically hindered by ... -
Elucidating the potential of novel class biphenyl-phenyl acetate, IDD-AN-A1, an inhibitor targeting Isocitrate Lyase in Mycobacterium tuberculosis: A target to lead approach.
Publication date: Mar 01, 2026 Isocitrate lyase (ICL), a pivotal enzyme of the glyoxylate shunt ... -
QuantiFERON-TB gold plus in people living with HIV: independence from CD4+ T-cell counts in a low TB-burden setting.
Publication date: Dec 31, 2026 Tuberculosis screening is recommended for people living with HIV. The ... -
Anoscrotal fistulas: causes and management in a 10-year French case series.
Publication date: Feb 04, 2026 Anoscrotal fistula is a rare variant of anal fistula, often ... -
Angioinvasive pulmonary mucormycosis presenting with massive haemoptysis secondary to pulmonary artery pseudoaneurysm.
Publication date: Feb 04, 2026 Pulmonary artery pseudoaneurysm (PAP) is a rare but potentially fatal ... -
Effectiveness of computer-aided detection chest X-ray screening for improving tuberculosis diagnostic yield in Chinese primary healthcare settings: study protocol for a prospective cluster randomised controlled trial.
Publication date: Feb 04, 2026 Tuberculosis (TB) remains a globally concerning infectious disease, and significant ... -
Investigation of the Effects of Oxidized Antigens on the T-Cell Response and the Epigenetic Reprogramming of Neutrophils in Lung Diseases – OXIGENE –
Publication date: Jan 27, 2026 The OXIGENE study is a research project that aims to ... -
Effect of Peer-led Educational Intervention on Treatment Outcomes Among Adults With Drug-susceptible Pulmonary Tuberculosis in South Omo and Ari Zone, Southern Ethiopia: A Protocol for a Cluster- Randomized Controlled Trial Study
Publication date: Jan 28, 2026 The study might come up with valuable findings to address ...