Tuberculosis
Tuberculosis (TB) is a contagious and potentially serious infectious disease caused by the bacterium Mycobacterium tuberculosis. It primarily affects the lungs but can also affect other parts of the body, such as the kidneys, spine, and brain.
TB spreads through the air when an infected individual coughs, sneezes, or speaks, releasing tiny droplets containing the bacteria into the air. When a person inhales these droplets, they can become infected with TB. However, it’s important to note that not everyone infected with the bacteria develops active TB. In many cases, the immune system is able to keep the bacteria in check, causing the infection to remain latent.
Latent TB infection means that the bacteria are present in the body but are inactive and do not cause any symptoms. People with latent TB are not contagious and cannot spread the disease to others. However, if the immune system becomes weakened, such as due to certain medical conditions or medications, latent TB can become active.
This magazine contains content which is gathered, validated, categorized, and supplied using a novel big data cyberinfrastructure technology that continually learns about Tuberculosis.
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Publication date: Jun 29, 2023 The objective of this study was to estimate the seroprevalence ...
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The seroprevalence of anti-Histoplasma capsulatum IgG antibody among pulmonary tuberculosis patients in seven referral tuberculosis hospitals in Indonesia.
Publication date: Sep 01, 2023 Histoplasma capsulatum exposure is rarely suspected in Indonesia. Pulmonary histoplasmosis ... -
Glycerol contributes to tuberculosis susceptibility in male mice with type 2 diabetes.
Publication date: Sep 20, 2023 Diabetes mellitus increases risk for tuberculosis disease and adverse outcomes. ... -
Viral Load and CD4 Markers as Determinants of Tuberculosis Coinfection Among People Living with HIV/AIDS in Papua Indonesia.
Publication date: Sep 20, 2023 Tuberculosis (TB) infection causes mortality among PLHIV, so the treatment ... -
Phenolic Substitution in Fidaxomicin: A Semisynthetic Approach to Antibiotic Activity Across Species.
Publication date: Sep 20, 2023 Fidaxomicin (Fdx) is a natural product antibiotic with potent activity ... -
In silico structural and mechanical insights into bedaquiline resistance associated with high-grade non-synonymous mutations in atpE, mmpR5, and pepQ.
Publication date: Sep 20, 2023 Clinical resistance against bedaquiline (BDQ) remains intractable to anti-tuberculosis therapies ... -
In silico studies of alkaloids and their derivatives against N-acetyltransferase EIS protein from Mycobacterium tuberculosis.
Publication date: Sep 20, 2023 Antibiotic resistance against Mycobacterium tuberculosis (M. tb. ) has been ... -
Assessment and validation of enrichment and target capture approaches to improve Mycobacterium tuberculosis WGS from direct patient samples.
Publication date: Sep 20, 2023 Within-host Mycobacterium tuberculosis (Mtb) diversity may detect antibiotic resistance or ... -
A retrospective analysis of the clinicopathological features of patients with tuberculous mastitis: A single institution’s experience.
Publication date: Sep 20, 2023 Tuberculosis remains a global health burden, especially in low- and ... -
A cluster of six respiratory cultures positive for Mycobacterium xenopi -Clinical characteristics and genomic characterization.
Publication date: Dec 01, 2023 Mycobacterium xenopi is a slow growing non-tuberculous mycobacterium (NTM) isolated ... -
Inadequate Lopinavir Concentrations With Modified 8-Hourly Lopinavir/Ritonavir 4:1 Dosing During Rifampicin-based Tuberculosis Treatment in Children Living With HIV.
Publication date: Oct 01, 2023 Lopinavir/ritonavir plasma concentrations are profoundly reduced when co-administered with rifampicin. ... -
Four months of tuberculosis (TB) treatment is non-inferior to the current 6-month treatment in drug-susceptible paediatric TB.
Publication date: Oct 01, 2023 Concepts Keywords Drugs Child Health Inferior Communicable Diseases Months Global ... -
What’s New in the Molecular Diagnosis of Childhood Tuberculosis?
Publication date: Oct 01, 2023 Concepts Keywords Childhood Childhood Diagnosis Clinical Dis Diagnosis Molecular Dis ... -
Incidence Rate of Tuberculosis Among Individuals With HIV in Africa Higher Than Estimated
Publication date: Sep 20, 2023 The incidence rate of tuberculosis and its associated factors among ... -
Identification of Hub Genes and Typing of Tuberculosis Infections Based on Autophagy-Related Genes.
Publication date: Sep 01, 2023 Tuberculosis (TB) caused by Mycobacterium tuberculosis is one of the ... -
Meropenem-vaborbactam restoration of first-line drugs’ efficacy and comparison of meropenem-vaborbactam-moxifloxacin versus BPaL MDR-TB regimen.
Publication date: Sep 17, 2023 . To identify alternative treatment regimens for multi-drug resistant tuberculosis ... -
AHL score for predicting mortality risk in patients with pulmonary tuberculosis.
Publication date: Sep 17, 2023 A clinically applicable mortality-risk prediction system for pulmonary tuberculosis may ... -
The impact of preventive treatment for multidrug- and rifampin-resistant tuberculosis exceeds trial-based estimates.
Publication date: Sep 19, 2023 Several clinical trials of tuberculosis preventive treatment (TPT) for household ... -
Plasmid-mediated drug resistance in mycobacteria: the tip of the iceberg?
Publication date: Sep 19, 2023 Macrolides, such as clarithromycin, are crucial in the treatment of ... -
Diagnostic performance of host protein signatures as a triage test for active pulmonary TB.
Publication date: Sep 19, 2023 The current four-symptom screen recommended by the World Health Organization ... -
MDA5 RNA sensing pathway activation by Mycobacterium tuberculosis promotes innate immune subversion and pathogen survival.
Publication date: Sep 19, 2023 Host cytosolic sensing of Mycobacterium tuberculosis (M. tb) RNA by ...