Tuberculosis
Tuberculosis (TB) is a contagious and potentially serious infectious disease caused by the bacterium Mycobacterium tuberculosis. It primarily affects the lungs but can also affect other parts of the body, such as the kidneys, spine, and brain.
TB spreads through the air when an infected individual coughs, sneezes, or speaks, releasing tiny droplets containing the bacteria into the air. When a person inhales these droplets, they can become infected with TB. However, it’s important to note that not everyone infected with the bacteria develops active TB. In many cases, the immune system is able to keep the bacteria in check, causing the infection to remain latent.
Latent TB infection means that the bacteria are present in the body but are inactive and do not cause any symptoms. People with latent TB are not contagious and cannot spread the disease to others. However, if the immune system becomes weakened, such as due to certain medical conditions or medications, latent TB can become active.
This magazine contains content which is gathered, validated, categorized, and supplied using a novel big data cyberinfrastructure technology that continually learns about Tuberculosis.
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Publication date: Dec 08, 2025 Mycobacterium tuberculosis, the etiological agent of tuberculosis, is a significant ...
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Rapidly Growing ALK-Negative NTRK3-Positive Inflammatory Myofibroblastic Tumour of the Lung.
Publication date: Dec 01, 2025 Inflammatory myofibroblastic tumours (IMT) are rare mesenchymal neoplasms that account ... -
Inhibition of de novo fatty acid synthesis in Mycobacterium tuberculosis.
Publication date: Dec 08, 2025 De novo fatty acid synthesis produces the acyl units needed ... -
ESAT-6 and CFP-10 reactive IgG in patients with tuberculosis inhibits intracellular bacteria.
Publication date: Dec 09, 2025 Perspectives beyond the CD4 T cell interferon (IFN)-γ paradigm are ... -
Immune response to co-administration of Bacillus Calmette-Guérin (BCG) and contraceptive vaccines in badgers (Meles meles).
Publication date: Dec 09, 2025 Controlling bovine tuberculosis (bTB) in livestock is often hindered by ... -
Effect of same-day HIV treatment initiation (SDI) on 1-year outcomes in low- and middle-income countries: systematic review and meta-analysis of randomised trials.
Publication date: Dec 10, 2025 Same-day initiation (SDI) of antiretroviral therapy is recommended for people ... -
Synthesis of S- or N-glycomimetics of D-galactono-1,4-lactone: inhibitors of a β-galactofuranosidase.
Publication date: Dec 10, 2025 In the search for β-galactofuranosidase inhibitors, the synthesis of 4-thio-D-galactonic ... -
Evaluation of stool-based testing to diagnose tuberculosis in children using the Truenat platform in routine settings in Nigeria.
Publication date: Dec 10, 2025 The World Health Organization (WHO) recommends testing stool with Xpert ... -
Diagnostic performance of the Sanity 2.0 assay to detect resistance to rifampicin, isoniazid, and fluoroquinolones in tuberculosis.
Publication date: Dec 10, 2025 Effective tuberculosis (TB) management relies on prompt diagnosis of Mycobacterium ... -
Evaluation of the Simple One-Step (SOS) stool method for Truenat MTB plus and Xpert MTB/XDR assay.
Publication date: Dec 10, 2025 Stool is a recommended sample for the diagnosis of Mycobacterium ... -
A Comparative Evaluation of Zero-Shot Performance of SAM, SAM2, MedSAM, and MedSAM2 Models on Lung Segmentation.
Publication date: Dec 10, 2025 Lung diseases require accurate and early diagnosis to ensure effective ... -
Mycobacterial respiratory chain enzymes and growth are inhibited by decylubiquinone.
Publication date: Dec 10, 2025 Aerobic organisms obtain energy by linking electron transfer from NADH ... -
Reported Tuberculosis Symptoms: An Inadequate Classifier of Disease State.
Publication date: Dec 10, 2025 Around half of people identified with tuberculosis (TB) during prevalence ... -
Neurosarcoidosis in Critical Care, Internal and Pulmonary Medicine: A Practical Approach.
Publication date: Dec 10, 2025 Neurosarcoidosis is a rare but clinically significant manifestation of sarcoidosis, ... -
Whole exome sequencing identifies rare variants involved in PPIX-metabolizing pathway in anti-TB drug-induced hepatitis.
Publication date: Dec 10, 2025 To screen and validate rare variants in the protoporphyrin IX ... -
Serum Omics Analysis Reveals Tissue Damage and Metabolic Reprogramming in Cavitary Pulmonary Tuberculosis.
Publication date: Dec 09, 2025 Cavitary pulmonary tuberculosis (cPTB) is the most destructive manifestation of ... -
Clinical characteristics, antimicrobial susceptibility patterns, and treatment outcomes of nontuberculous mycobacterial diseases in eastern China: a retrospective cohort study (2019-2022).
Publication date: Dec 09, 2025 Nontuberculous mycobacteria (NTM) are opportunistic pathogens, and the global incidence ... -
Consensus of Korean Asthma Study Group on Definition of Clinical Remission in Severe Asthma: A Modified Delphi Study.
Publication date: Dec 09, 2025 Asthma remission has recently emerged as an aspirational treatment goal, ... -
Whole-Genome and Targeted Sequencing of 75 Drug-Resistant Mycobacterium tuberculosis Clinical Isolates in South Korea.
Publication date: Dec 09, 2025 Tuberculosis (TB), an infectious disease caused by Mycobacterium tuberculosis (M. ... -
Molecular links between tuberculosis and lung cancer: pathogenesis and therapeutic challenges.
Publication date: Dec 09, 2025 Tuberculosis (TB) and lung cancer, two leading global health burdens, ... -
Effect of Isoniazid Resistance on Treatment Outcome Among People With Pulmonary Tuberculosis in Korea.
Publication date: Dec 08, 2025 Isoniazid resistance is the most common type of ant-tuberculosis drug ...