Tuberculosis
Tuberculosis (TB) is a contagious and potentially serious infectious disease caused by the bacterium Mycobacterium tuberculosis. It primarily affects the lungs but can also affect other parts of the body, such as the kidneys, spine, and brain.
TB spreads through the air when an infected individual coughs, sneezes, or speaks, releasing tiny droplets containing the bacteria into the air. When a person inhales these droplets, they can become infected with TB. However, it’s important to note that not everyone infected with the bacteria develops active TB. In many cases, the immune system is able to keep the bacteria in check, causing the infection to remain latent.
Latent TB infection means that the bacteria are present in the body but are inactive and do not cause any symptoms. People with latent TB are not contagious and cannot spread the disease to others. However, if the immune system becomes weakened, such as due to certain medical conditions or medications, latent TB can become active.
This magazine contains content which is gathered, validated, categorized, and supplied using a novel big data cyberinfrastructure technology that continually learns about Tuberculosis.
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Publication date: Oct 01, 2024 The challenges to effective tuberculosis (TB) disease control are considerable, ...
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Advances in tuberculosis biomarkers: unravelling risk factors, active disease and treatment success.
Publication date: Oct 01, 2024 Tuberculosis (TB) is a major global health threat and demands ... -
The Evolution of Tuberculosis Community Transmission Science and its Ethical and Legal Constructs.
Publication date: Dec 11, 2024 Concepts Keywords Community Community Evolution Constructs Infect Dis Legal Ethical ... -
Phytocompounds hesperidin, rebaudioside a and rutin as drug leads for the treatment of tuberculosis targeting mycobacterial phosphoribosyl pyrophosphate synthetase.
Publication date: Dec 11, 2024 The main aim of this study is to address the ... -
Promoting the Efficacy of Deferiprone-Gallium-Protoporphyrin (IX) against Mycobacterium abscessus Intracellular Infection with Lipid Liquid Crystalline Nanoparticles.
Publication date: Dec 11, 2024 Nontuberculous mycobacteria (NTM) are among the recalcitrant bacterial strains that ... -
Polycytotoxic T cells mediate antimicrobial activity against intracellular Mycobacterium tuberculosis.
Publication date: Dec 11, 2024 Protection against infections with intracellular bacteria requires the interaction of ... -
Comparison of the molecular FluoroType Mycobacteria VER 1.0 and the Maldi BioTyper Mycobacteria assays for the identification of non-tuberculous mycobacteria.
Publication date: Dec 11, 2024 Accurate identification of non-tuberculous mycobacterial (NTM) species is crucial for ... -
Identification of novel fructose 1,6-bisphosphate aldolase inhibitors against tuberculosis: QSAR, molecular docking, and molecular dynamics simulation-based analysis of DrugBank compounds.
Publication date: Dec 11, 2024 Global initiatives aim to curb tuberculosis (TB) by developing efficient ... -
An unusual activity of mycobacterial MutT1 Nudix hydrolase domain as a protein phosphatase regulates nucleoside diphosphate kinase function.
Publication date: Dec 11, 2024 MutT proteins are Nudix hydrolases characterized by the presence of ... -
Multiloculated pyopneumothorax with subcutaneous emphysema and pneumomediastinum in a tuberculosis patient.
Publication date: Dec 01, 2024 Pulmonary tuberculosis with the simultaneous development of the complications of ... -
Rasmussen aneurysm in a patient with pulmonary tuberculosis.
Publication date: Dec 01, 2024 Rasmussen aneurysm is a rare complication of tuberculosis, where a ... -
Port site tuberculosis after laparoscopic cholecystectomy in resource limiting setup: Case series and literature review.
Publication date: Dec 08, 2024 Laparoscopic cholecystectomy has become the gold standard for treating symptomatic ... -
Is There a Genuine Correlation Between Blood Glucose Control and Anti-tuberculosis Drug Concentrations, or Is it Merely an Illusion?
Publication date: Dec 09, 2024 Concepts Keywords Blood Anti Drug Blood Genuine Clin Glucose Concentrations ... -
Whole genome sequence of a Mycobacterium tuberculosis M64 isolate harboring extensive deletions, including the katG-containing region.
Publication date: Dec 10, 2024 Clinical isolates of Mycobacterium tuberculosis M64 strain from South Korea ... -
Immunological mechanisms of tuberculosis susceptibility in TB-infected individuals with type 2 diabetes mellitus: insights from mycobacterial growth inhibition assay and cytokine analysis.
Publication date: Dec 10, 2024 Several studies have highlighted the increased risk of active tuberculosis ... -
Early bactericidal activity of sitafloxacin against pulmonary tuberculosis.
Publication date: Dec 10, 2024 Sitafloxacin is a quinolone broad-spectrum antimicrobial agent, and its pharmacologic ... -
Serpiginous-Like Choroiditis with ANCA-PR3 Vasculitis in a Patient from Endemic Country: A Complex Phenotypic, Immunological and Epidemiological Puzzle.
Publication date: Dec 10, 2024 To report a complex case of serpiginous-like choroiditis (SLC) in ... -
Concomitant Nasopharyngeal and Otomastoid Tuberculosis: a Report of 3 Cases and a Review of Literature.
Publication date: Dec 10, 2024 Objective: Concomitant nasopharyngeal and otomastoid tuberculosis (TB) is an extremely ... -
Performance of urine Xpert MTB/RIF ultra in a tuberculosis screening strategy in hospitalized patients with advanced HIV disease: Results from an implementation initiative in Brazil.
Publication date: Dec 10, 2024 To evaluate the performance of Xpert MTB/RIF Ultra testing in ... -
The Frequency and Incidence of QT Prolongation with Extended Use of Bedaquiline or Delamanid in a Large, Multi-Country MDR/RR-TB Cohort.
Publication date: Dec 10, 2024 The 2022 WHO guidelines on multi-drug/rifampicin resistant tuberculosis (MDR/RR-TB) recommend ... -
Furamidine-induced autophagy exerts an anti-mycobacterial effect in a SIRT1-pAMPK-FOXO3a-dependent manner by elevation of intracellular Ca level expression.
Publication date: Jan 01, 2025 Mycobacterium tuberculosis (M. tb), the etiological agent of tuberculosis (TB), ...