Search Results for: next generation sequencing

November 27, 2023November 27, 2023

Targeted next-generation sequencing technology showed great potential in identifying spinal tuberculosis and predicting the drug resistance.

Publication date: Dec 01, 2023 Concepts Keywords Drug Drug Infect Generation Potential Great Spinal Identifying Tuberculosis Infect Potential Predicting Resistance Sequencing Showed Spinal Targeted Tuberculosis Semantics Type Source Name disease ... Read more

November 18, 2023November 18, 2023

Microbiome Alteration in Lung Tissues of Tuberculosis Patients Revealed by Metagenomic Next-Generation Sequencing and Immune-Related Transcriptional Profile Identified by Transcriptome Sequencing.

Tuberculosis Literature

Publication date: Nov 17, 2023 This study explored alterations in the respiratory microbiome and transcriptome after Mycobacterium tuberculosis infection in tuberculosis (TB) patients. Metagenomic next-generation sequencing (mNGS) was adopted to ... Read more

November 7, 2023November 7, 2023

Metagenomic next-generation sequencing for diagnosis of infectious encephalitis and meningitis: a retrospective study of 90 patients.

Tuberculosis Literature

Publication date: Nov 06, 2023 Infections of the central nervous system (CNS) are potentially life-threatening and can cause serious morbidity. We evaluated the clinical value of metagenomic next-generation sequencing (mNGS) ... Read more

September 10, 2023September 10, 2023

Diagnostic performance of metagenomic next-generation sequencing and conventional microbial culture for spinal infection: a retrospective comparative study.

Tuberculosis Literature

Publication date: Sep 09, 2023 The study evaluated the diagnostic performance of metagenomic next-generation sequencing (mNGS) as a diagnostic test for biopsy samples from patients with suspected spinal infection (SI) ... Read more

November 24, 2023November 24, 2023

Initial experiences with Mycobacterium tuberculosis DNA extraction for downstream Deeplex Myc-TB targeted deep sequencing in a high burden setting.

Tuberculosis News

Publication date: Nov 22, 2023 The propensity for M. tuberculosis to develop resistance and the lack of clinical tools for the rapid determination of such resistance has long significantly complicated ... Read more

November 8, 2023November 8, 2023

The application of nanopore targeted sequencing for pathogen diagnosis in bronchoalveolar lavage fluid of patients with pneumonia: a prospective multicenter study.

Tuberculosis Literature

Publication date: Nov 07, 2023 To evaluate the value of nanopore targeted sequencing in diagnosing pneumonia pathogens. This large-scale multicentre prospective study performed in 8 hospitals across China from April ... Read more

October 29, 2023

Composition of pathogenic microorganism in chronic osteomyelitis based on metagenomic sequencing and its application value in etiological diagnosis.

Tuberculosis Literature

Publication date: Oct 28, 2023 Traditionally, conventional microbiological culture methods have been used to detect pathogenic microorganisms in chronic osteomyelitis. However, these methods have been found to have a low ... Read more

November 25, 2023November 25, 2023

Two-stage tuberculosis diagnostics: combining centrifugal microfluidics to detect TB infection and Inh and Rif resistance at the point of care with subsequent antibiotic resistance profiling by targeted NGS.

Tuberculosis Literature

Publication date: Nov 24, 2023 Globally, tuberculosis (TB) remains the deadliest bacterial infectious disease, and spreading antibiotic resistances is the biggest challenge for combatting the disease. Rapid and comprehensive diagnostics ... Read more

November 16, 2023November 16, 2023

Clinical, epidemiological, and molecular investigation of Kyasanur forest disease from Karnataka state, India during 2018-2019.

Chikungunya Literature

Publication date: Nov 15, 2023 In this study, we carried out an investigation of Kyasanur Forest Disease (KFD) suspected human cases reported in Karnataka state, India from December 2018 to ... Read more

October 26, 2023October 26, 2023

A case report on Mycobacterium houstonense infection after total hip arthroplasty.

Tuberculosis Literature

Publication date: Oct 25, 2023 Mycobacterium houstonense is a category of rapidly growing mycobacteria that is gram-positive, acid-fast, polycrystalline, and non-spore-forming. There have been few reports of human infection caused ... Read more