Search Results for: defects

November 24, 2023November 24, 2023

Diagnosis of inflammatory myofibroblastic tumor in a pediatric patient initially suspected of tuberculosis.

Publication date: Nov 24, 2023 Symptoms of inflammatory myofibroblastic tumor (IMT) are atypical, and histopathological misdiagnosis of IMT is still inevitable. Here we present a pediatric case that an eight-year-old ... Read more

November 12, 2023November 12, 2023

Mechanopathology of biofilm-like Mycobacterium tuberculosis cords.

Tuberculosis Literature

Publication date: Nov 09, 2023 Mycobacterium tuberculosis (Mtb) cultured axenically without detergent forms biofilm-like cords, a clinical identifier of virulence. In lung-on-chip (LoC) and mouse models, cords in alveolar cells ... Read more

November 3, 2023November 3, 2023

Detection of coinfection with Primate Erythroparvovirus 1 and arboviruses (DENV, CHIKV and ZIKV) in individuals with acute febrile illness in the state of Rio Grande do Norte in 2016.

Chikungunya Literature

Publication date: Nov 02, 2023 Arthropod-borne viruses, known as arboviruses, pose substantial risks to global public health. Dengue (DENV), Chikungunya (CHIKV) and Zika (ZIKV) viruses stand out as significant concerns ... Read more

October 28, 2023October 28, 2023

Mitochondrial metabolism in alveolar macrophages of patients infected with HIV, tuberculosis (TB) and HIV/TB.

Tuberculosis Literature

Publication date: Oct 26, 2023 Tuberculosis (TB) is one of the most common opportunistic infections and is a leading cause of mortality in patients with human immunodeficiency virus (HIV) and ... Read more

October 24, 2023October 24, 2023

Intrabacterial lipid inclusion-associated proteins: A core machinery conserved from saprophyte Actinobacteria to the human pathogen Mycobacterium tuberculosis.

Tuberculosis Literature

Publication date: Oct 23, 2023 Mycobacterium tuberculosis (Mtb), the aetiologic agent of tuberculosis (TB), stores triacylglycerol (TAG) in the form of intrabacterial lipid inclusions (ILI) to survive and chronically persist ... Read more

October 15, 2023October 15, 2023

Structural basis for triacylglyceride extraction from mycobacterial inner membrane by MFS transporter Rv1410.

Tuberculosis Literature

Publication date: Oct 13, 2023 Mycobacterium tuberculosis is protected from antibiotic therapy by a multi-layered hydrophobic cell envelope. Major facilitator superfamily (MFS) transporter Rv1410 and the periplasmic lipoprotein LprG are ... Read more

October 6, 2023October 6, 2023

Arboviral Risk Associated with Solid Organ and Hematopoietic Stem Cell Grafts: The Prophylactic Answers Proposed by the French High Council of Public Health in a National Context.

Chikungunya Literature

Publication date: Aug 22, 2023 Diseases caused by arboviruses are on the increase worldwide. In addition to arthropod bites, most arboviruses can be transmitted via accessory routes. Products of human ... Read more

October 5, 2023October 5, 2023

Intravenous administration of BCG in mice promotes natural killer and T cell-mediated antitumor immunity in the lung.

Tuberculosis Literature

Publication date: Oct 04, 2023 Intravesical administration of Bacillus Calmette-GucE9rin (BCG) was one of the first FDA-approved immunotherapies and remains a standard treatment for bladder cancer. Previous studies have demonstrated ... Read more

September 29, 2023

Epidemiological features and temporal trends of HIV-negative tuberculosis burden from 1990 to 2019: a retrospective analysis based on the Global Burden of Disease Study 2019.

Tuberculosis Literature

Publication date: Sep 28, 2023 This study aimed to analyse the burden and temporal trends of tuberculosis (TB) incidence and mortality globally, as well as the association between mortality-to-incidence ratio ... Read more

September 28, 2023September 28, 2023

A tRNA modification in Mycobacterium tuberculosis facilitates optimal intracellular growth.

Tuberculosis Literature

Publication date: Sep 27, 2023 Diverse chemical modifications fine-tune the function and metabolism of tRNA. Although tRNA modification is universal in all kingdoms of life, profiles of modifications, their functions, ... Read more