Search Results for: bioinformatics

November 23, 2023November 23, 2023

Identifying the Interaction Between Tuberculosis and SARS-CoV-2 Infections via Bioinformatics Analysis and Machine Learning.

Publication date: Nov 22, 2023 The number of patients with COVID-19 caused by severe acute respiratory syndrome coronavirus 2 is still increasing. In the case of COVID-19 and tuberculosis (TB), ... Read more

October 19, 2023October 19, 2023

Bioinformatics-led discovery of ferroptosis-associated diagnostic biomarkers and molecule subtypes for tuberculosis patients.

Tuberculosis Literature

Publication date: Oct 19, 2023 Ferroptosis is closely associated with the pathophysiological processes of many diseases, such as infection, and is characterized by the accumulation of excess lipid peroxides on ... Read more

September 10, 2023September 10, 2023

Integrated bioinformatics analysis of dendritic cells hub genes reveal potential early tuberculosis diagnostic markers.

Tuberculosis Literature

Publication date: Sep 08, 2023 Dendritic cells (DCs) are most potent antigen-processing cells and play key roles in host defense against Mycobacterium tuberculosis (MTB) infection. In this study, hub genes ... Read more

November 24, 2023November 24, 2023

Functional Whole Genome Screen of Nutrient-Starved Mycobacterium tuberculosis Identifies Genes Involved in Rifampin Tolerance.

Tuberculosis Literature

Publication date: Sep 09, 2023 Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), poses a global health challenge and is responsible for over a million deaths each year. Current ... Read more

November 16, 2023November 16, 2023

Deep learning on longitudinal CT scans: automated prediction of treatment outcomes in hospitalized tuberculosis patients.

Tuberculosis Literature

Publication date: Nov 17, 2023 Three deep learning (DL)-based prediction models (PMs) using longitudinal CT images were developed to predict tuberculosis (TB) treatment outcomes. The internal dataset consists of 493 ... Read more

November 5, 2023November 5, 2023

In silico prediction of interaction between Nipah virus attachment glycoprotein and host cell receptors Ephrin-B2 and Ephrin-B3 in domestic and peridomestic mammals.

Nipah Virus Literature

Publication date: Nov 02, 2023 Nipah virus (NiV) is a lethal bat-borne zoonotic virus that causes mild to acute respiratory distress and neurological manifestations in humans with a high mortality ... Read more

November 3, 2023November 3, 2023

Vaccines based on the Fusion protein consensus sequence protected Syrian hamsters from Nipah virus infection.

Nipah Virus Literature

Publication date: Nov 02, 2023 Nipah virus (NiV), a bat-borne paramyxovirus, results in neurological and respiratory diseases with high mortality in humans and animals. Developing vaccines is crucial against the ... Read more

November 1, 2023November 1, 2023

Detection of microRNAs expression signatures in vitreous humor of intraocular tuberculosis.

Tuberculosis Literature

Publication date: Oct 31, 2023 MicroRNA (miRNA) expression analysis has been shown to provide them as biomarkers in several eye diseases and has a regulatory role in pathogenesis. However, miRNA ... Read more

October 24, 2023October 24, 2023

fastlin: an ultra-fast program for Mycobacterium tuberculosis complex lineage typing.

Tuberculosis Literature

Publication date: Oct 23, 2023 Fastlin is a bioinformatics tool designed for rapid MTBC lineage typing. It utilises an ultra-fast alignment-free approach to detect previously identified barcode single nucleotide polymorphisms ... Read more

October 22, 2023October 22, 2023

The heparin-binding haemagglutinin protein of Mycobacterium tuberculosis is a nucleoid-associated protein.

Tuberculosis Literature

Publication date: Oct 19, 2023 Nucleoid-associated proteins (NAPs) regulate multiple cellular processes such as gene expression, virulence, and dormancy throughout bacterial species. NAPs help in the survival and adaptation of ... Read more