Search Results for: Mycobacterium tuberculosis

Crystallographic fragment-binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate-channeling path between them.

Crystallographic fragment-binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate-channeling path between them.

Tuberculosis Literature
Publication date: Aug 01, 2024 The Mycobacterium tuberculosis trifunctional enzyme (MtTFE) is an αβ tetrameric enzyme in which the α-chain harbors the 2E-enoyl-CoA hydratase (ECH) and 3S-hydroxyacyl-CoA dehydrogenase (HAD) active ... Read more
A composite reference standard is needed for bedaquiline antimicrobial susceptibility testing for Mycobacterium tuberculosis complex.

A composite reference standard is needed for bedaquiline antimicrobial susceptibility testing for Mycobacterium tuberculosis complex.

Tuberculosis Literature
Publication date: Jul 01, 2024 Concepts Keywords Bedaquiline Antitubercular Agents Complex Antitubercular Agents Drugs bedaquiline Mycobacterium Diarylquinolines Tuberculosis Diarylquinolines Humans Microbial Sensitivity Tests Mycobacterium tuberculosis Reference Standards Tuberculosis, Multidrug-Resistant Semantics ... Read more