Search Results for: Biomarkers
Advances in tuberculosis biomarkers: unravelling risk factors, active disease and treatment success.
Tuberculosis Literature
Publication date: Oct 01, 2024 Tuberculosis (TB) is a major global health threat and demands improved diagnostic and treatment monitoring methods. Conventional diagnostics, such as sputum smear microscopy and culture, ... Read more
Identification of diagnostic biomarkers and molecular subtype analysis associated with m6A in Tuberculosis immunopathology using machine learning.
Tuberculosis Literature
Publication date: Dec 02, 2024 Tuberculosis (TB), ranking just below COVID-19 in global mortality, is a highly complex infectious disease involving intricate immunological molecules, diverse signaling pathways, and multifaceted immune ... Read more
Combining bioinformatics and machine learning to identify diagnostic biomarkers of TB associated with immune cell infiltration.
Tuberculosis Literature
Publication date: Dec 01, 2024 The asymptomatic nature of tuberculosis (TB) during its latent phase, combined with limitations in current diagnostic methods, makes accurate diagnosis challenging. This study aims to ... Read more
Candidate serum protein biomarkers for active pulmonary tuberculosis diagnosis in tuberculosis endemic settings.
Tuberculosis Literature
Publication date: Nov 21, 2024 Identification of non-sputum diagnostic markers for tuberculosis (TB) is urgently needed. This exploratory study aimed to discover potential serum protein biomarkers for the diagnosis of ... Read more
Unlocking the Diagnostic Potential: A Systematic Review of Biomarkers in Spinal Tuberculosis.
Tuberculosis Literature
Publication date: Aug 25, 2024 Background/Objectives: Spinal tuberculosis (STB) is frequently misdiagnosed due to the multitude of symptoms it presents with. This review aimed to investigate the biomarkers that have ... Read more
Host blood protein biomarkers to screen for tuberculosis disease: a systematic review and meta-analysis.
Tuberculosis Literature
Publication date: Oct 24, 2024 Non-sputum tests are needed to improve tuberculosis (TB) diagnosis and close the diagnostic gap. The World Health Organization’s target product profile (TPP) for point-of-care (POC) ... Read more
Assessing the risk of TB progression: Advances in blood-based biomarker research.
Tuberculosis Literature
Publication date: Mar 01, 2025 This review addresses the significant advancements in the identification of blood-based prognostic biomarkers for tuberculosis (TB), highlighting the importance of early detection to prevent disease ... Read more
OLAgen: A Software Tool for Reagent Design to Expand Access to Single Nucleotide Variant Detection by the Oligonucleotide Ligation Assay.
Tuberculosis Literature
Publication date: Jan 14, 2025 Single nucleotide variations (SNVs) and polymorphisms (SNPs) are characteristic biomarkers in various biological contexts, including pathogen drug resistances and human diseases. Tools that lower the ... Read more
Identifying plasma exosome antigens as a potential diagnostic biomarker for tuberculosis disease.
Tuberculosis Literature
Publication date: Jan 14, 2025 Exosome is a small extracellular vesicle with a diameter of 30 to 150 nm that is secreted by cells. Mtb and other bacteria can also ... Read more