Epidemiology and clinical outcomes in skin and soft tissue nontuberculous mycobacteria infections: A retrospective study.

Epidemiology and clinical outcomes in skin and soft tissue nontuberculous mycobacteria infections: A retrospective study.

Publication date: Mar 01, 2025

Nontuberculous mycobacteria (NTM) are emerging pathogens responsible for increasing skin and soft tissue infections (SSTIs) globally. However, the diagnosis and treatment of NTM SSTIs face significant challenges due to the lack of standardized guidelines. This study reviewed the clinical characteristics, diagnostic challenges, and treatment outcomes of NTM SSTIs in a large cohort from a tertiary referral center in Beijing, China. We retrospectively reviewed 142 patients diagnosed with NTM SSTIs at a tertiary hospital from 2014 to 2023. Data collected included clinical presentation, microbiologic and histopathologic findings, diagnostic methods, treatment regimens, and outcomes. The patients were categorized based on NTM species, and immunocompromised status. The cohort included patients with various NTM species, with M. marinum, M. avium complex (MAC), and M. abscessus complex (MABC) being the most common. The number of patients with NTM infections increased annually (p 

Concepts Keywords
Annually Adult
Avium Aged
China Anti-Bacterial Agents
Immunocompromised Anti-Bacterial Agents
Mycobacteria Antimicrobial susceptibility testing
China
Female
Humans
Immunocompromised Host
Male
Middle Aged
Mycobacterium Infections, Nontuberculous
Nontuberculous Mycobacteria
Nontuberculous mycobacteria
Retrospective Studies
Retrospective studies
Skin Diseases, Bacterial
Skin infections
Soft Tissue Infections
Soft tissue infections
Tertiary Care Centers
Treatment Outcome
Young Adult

Semantics

Type Source Name
disease MESH infections
disease MESH soft tissue infections
disease IDO susceptibility
disease MESH Immunocompromised Host
disease MESH Mycobacterium Infections Nontuberculous
disease MESH Skin Diseases Bacterial

Original Article

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