The effects of stigma and social support on the health-related quality of life of people with drug resistance tuberculosis in Lagos, Nigeria.

The effects of stigma and social support on the health-related quality of life of people with drug resistance tuberculosis in Lagos, Nigeria.

Publication date: Feb 18, 2025

This study assessed the effects of TB stigma and social support on the health-related quality of life (HRQoL) of people living with drug-resistant tuberculosis (DR-TB) in Lagos, Nigeria. A cross-sectional study was conducted in five DR-TB treatment centres in Lagos, Nigeria, between September and December 2023. A total of 203 adults on DR-TB treatment were recruited to complete a questionnaire including the Redwood DR-TB stigma scale, the Functional Assessment of Chronic Illness Therapy-TB (FACCIT) scale, and the Multidimensional Scale of Perceived Social Support (MSPSS). Student ‘t’ test/one-way ANOVA, Pearson’s correlation, and hierarchical linear regression analysis were conducted to explore the factors associated with HRQoL and the relationships between stigma, social support, and HRQoL. The mean overall HRQoL was 41. 1 +/- 12. 9 among people with DR-TB. The HRQoL score of the physical domain was the lowest (25. 8 +/- 13. 8). Participants who were young, male, single, with higher education, and HIV-negative had higher HRQoL than their counterparts (p 

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Concepts Keywords
Adults Nigeria
Nigeria Social support
Redwood TB-stigma
Therapy
Tuberculosis

Semantics

Type Source Name
disease IDO quality
disease MESH tuberculosis
pathway KEGG Tuberculosis
disease MESH drug-resistant tuberculosis
disease MESH Chronic Illness
disease MESH stigma social
drug DRUGBANK Coenzyme M
disease MESH morbidity
disease MESH psychological distress
disease IDO country
drug DRUGBANK Trestolone
drug DRUGBANK Polyethylene glycol
disease MESH Leprosy
disease IDO assay
disease MESH AIDs
disease MESH multiple sclerosis
disease MESH Parkinson’s disease
disease MESH rheumatoid arthritis
pathway KEGG Rheumatoid arthritis
drug DRUGBANK Aspartame
disease MESH marital status
drug DRUGBANK Ethanol
disease IDO facility
disease MESH educational status
drug DRUGBANK Esomeprazole
disease IDO process
disease MESH Comorbidity
disease MESH infection
disease MESH depression
disease MESH anxiety
disease IDO intervention
disease MESH privacy
pathway REACTOME Reproduction
disease MESH hypoventilation
disease MESH Infectious Diseases
disease MESH pulmonary tuberculosis
drug DRUGBANK Rifampicin
disease IDO site
disease MESH oral cancer
disease MESH hepatitis
drug DRUGBANK Spinosad
disease MESH Lung Diseases
disease MESH schizophrenia
disease MESH king’s evil
disease IDO history
disease MESH scrofula

Original Article

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