Pulmonary Complications of Biological Therapies in Inflammatory and Autoimmune Diseases.

Pulmonary Complications of Biological Therapies in Inflammatory and Autoimmune Diseases.

Publication date: Mar 01, 2025

Infective and noninfective pulmonary complications occur with biologic agents and targeted small molecule inhibitors used to treat immune-mediated inflammatory conditions. The most common lower respiratory tract infection is bacterial pneumonia. Opportunistic infections including tuberculosis can also occur at increased rates depending on the immunosuppressive agent, specific disease, and epidemiologic background of the patient. The most common noninfectious sequela is drug-induced interstitial lung disease.

Concepts Keywords
Biologic Autoimmune disease
Immunosuppressive Autoimmune Diseases
Increased Biological Therapy
Noninfective Biologics
Pneumonia Humans
Immunocompromised host
Immunosuppressive Agents
Immunosuppressive Agents
Immunosuppressive agents
Lung Diseases
Lung Diseases, Interstitial
Pulmonary complications
Pulmonary infections

Semantics

Type Source Name
disease MESH Complications
disease MESH Autoimmune Diseases
disease MESH bacterial pneumonia
disease MESH Opportunistic infections
disease MESH tuberculosis
pathway KEGG Tuberculosis
disease MESH interstitial lung disease
disease MESH Immunocompromised host
disease MESH Lung Diseases
disease MESH infections

Original Article

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