Interferon-gamma release assays as a tool for differential diagnosis of gastrointestinal tuberculosis.

Publication date: Sep 26, 2024

In this editorial, we comment on an article published in a recent issue of the World Journal of Clinical Cases. There is a pressing need for reliable tools for diagnosing tuberculosis (TB) of the gastrointestinal tract. Despite advancements in the diagnosis and treatment, TB remains a global health challenge. Ali et al demonstrated that TB may mimic gastrointestinal conditions, such as gastric outlet obstruction, causing a delay in the diagnosis. Furthermore, the latter complication is frequently observed during infections, including Helicobacter pylori, and rarely is related to TB, as in the presented case. In line with this, we think that laboratory tests based on interferon-gamma release assays can be a helpful tool for diagnosing latent TB paced in the gastrointestinal tract. Innovative strategies and approaches for diagnosing latent/active extra pulmonary TB are crucial for establishing the diagnosis early and enhancing treatment strategies to mitigate the global burden of TB.

Concepts Keywords
Gastric Case report
Global Gastric outlet obstruction
Helpful Gastrointestinal tuberculosis
Laboratory IGRA
Tuberculosis Interferon-gamma release assay
Primary gastroduodenal tuberculosis
Tuberculosis

Semantics

Type Source Name
pathway REACTOME Release
disease MESH gastrointestinal tuberculosis
disease MESH tuberculosis
pathway KEGG Tuberculosis
disease MESH gastric outlet obstruction
disease MESH infections
disease IDO assay

Original Article

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