Publication date: Sep 16, 2024
The latent tuberculosis infection (LTBI) burden is still unclear in schoolchildren and adolescents in China. Previous study and daily surveillance data indicate a LTBI detection gap. The research objective was to evaluate the LTBI burden and detection gap among schoolchildren and adolescents in China. A cross-sectional study was conducted among 69,667 schoolchildren and adolescents in Chongqing, China between September 2022 and December 2023 implemented by Chongqing Municipal Institute of Tuberculosis using tuberculin skin test (TST) and creation tuberculin skin test (C-TST). To evaluate the LTBI detection gap, the pulmonary tuberculosis (PTB) screening data implemented by Chongqing Municipal Institute of Tuberculosis have been compared with the data in 2021 implemented by community-level medical and health care institutions. The LTBI prevalence rate using TST and C-TST implemented by Chongqing Municipal Institute of Tuberculosis was 12. 8% (95%CI, 12. 5-13%) and 6. 4% (95%CI, 6-6. 8%) respectively. The LTBI prevalence rate by Chongqing Municipal Institute of Tuberculosis was 9. 6% higher than that by community-level medical and health care institutions (χ = 2931. 9, P
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Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | latent tuberculosis infection |
| disease | MESH | Tuberculosis |
| pathway | KEGG | Tuberculosis |
| disease | MESH | pulmonary tuberculosis |
| pathway | REACTOME | Reproduction |
| disease | MESH | Infectious Diseases |
| drug | DRUGBANK | Coenzyme M |
| disease | MESH | death |
| disease | IDO | intervention |
| drug | DRUGBANK | Medical air |
| disease | MESH | infection |
| drug | DRUGBANK | BCG vaccine |
| drug | DRUGBANK | Pentaerythritol tetranitrate |
| disease | MESH | erythema |
| disease | IDO | process |
| disease | MESH | allergic reactions |
| disease | MESH | anaphylactic shock |
| disease | MESH | educational level |
| disease | IDO | history |
| disease | IDO | protein |
| drug | DRUGBANK | Methionine |
| drug | DRUGBANK | Adenosine |
| disease | IDO | quality |
| drug | DRUGBANK | Trestolone |
| disease | MESH | morbidity |
| drug | DRUGBANK | Etoperidone |
| drug | DRUGBANK | Guanosine |
| disease | MESH | latent infection |