Publication date: Sep 09, 2024
Respiratory microbiota is closely related to tuberculosis (TB) initiation and progression. However, the dynamic changes of respiratory microbiota during treatment and its association with TB progression remains unclear. A total of 16 healthy individuals and 16 TB patients (10 drug-sensitive TB (DS-TB) and 6 drug-resistant TB (DR-TB)) were recruited. Sputum samples were collected at baseline for all anticipants and after anti-TB treatment at Month-6 for TB patients. High throughput 16 S RNA sequencing was used to characterize the respiratory microbiota composition. Compared to the healthy individuals, TB patients exhibited lower respiratory microbiota diversity (p
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | pulmonary tuberculosis |
| disease | MESH | tuberculosis |
| pathway | KEGG | Tuberculosis |
| disease | IDO | bacteria |
| disease | MESH | Tuberculosis Multidrug-Resistant |